Tag: cannabis

  • Multiple Cannabis Use Methods May Indicate Addiction Risk

    Cannabis Use Patterns
    Photo Credit: Unsplash+

    Today, cannabis consumption extends beyond just smoking. People now choose from options like vaping, ingesting in foods or beverages, or inhaling vaporized concentrates. A recent study in the U.S. suggests that the variety of methods someone uses may reveal important details about their usage habits.

    Researchers at NYU Langone Health discovered that adults who utilize multiple forms of cannabis are significantly more likely to use it daily. They also have a higher chance of displaying signs of cannabis use disorder, a condition characterized by problematic, hard-to-control use that causes significant issues.

    With changing laws and shifting public attitudes, cannabis use has become more prevalent across the United States. Recent national estimates indicate that tens of millions of Americans aged 12 and older have used cannabis within the past month.

    Cannabis products deliver effects through various methods. Smoking acts quickly, whereas edible products tend to have delayed but longer-lasting effects. Vaping heats cannabis without combustion, and dabbing involves inhaling vaporized concentrates with high THC levels—the primary compound responsible for intoxication.

    The study analyzed data from 17,732 adults who reported using cannabis in the month prior, sourced from the 2022–2023 National Survey on Drug Use and Health—an extensive survey tracking substance use nationwide.

    Instead of isolating each consumption method, researchers examined how different methods co-occurred, identifying common usage patterns among users.

    Approximately 48% of participants primarily smoked cannabis. An additional 21% commonly combined smoking and vaping, while 17% mainly consumed edible cannabis products.

    The remaining 14% formed what the researchers labeled a polymodal group—individuals who used nearly all available forms rather than sticking to just one.

    This smaller group stood out in terms of usage frequency. Nearly half of those employing multiple methods reported daily use.

    In contrast, daily use was less prevalent in other groups—about 28% among mostly smokers, 31% among those who smoked and vaped, and only 13% among primarily edible consumers.

    When it came to cannabis use disorder, the differences were even more striking. About 67% of the multiple-method users met criteria for the disorder, compared to 36% of primary smokers, 47% of those who combined smoking and vaping, and 15% of edible users.

    This suggests that using cannabis through various methods may be a key indicator of heavier, potentially problematic use.

    Lead researcher Dr. Omar El-Shahawy recommends that healthcare providers consider asking patients about how they consume cannabis, not just whether they use it. Patients who frequently switch between methods might require closer evaluation of their use patterns.

    The study also found demographic differences. Young adults aged 18 to 25 were more common among those who smoked and vaped or used multiple forms. Meanwhile, women and college graduates were more often among those who primarily used edibles.

    Additionally, cannabis users who smoked also tended to smoke cigarettes more often than those who mainly vaped or ate cannabis. Senior author Joseph Palamar expressed concern about this overlap, as combining smoking tobacco and cannabis can increase exposure to harmful chemicals and lung irritants.

    The research was published online on August 8, 2026, in the journal Addictive Behaviors. The authors plan to explore why individuals prefer certain forms—such as whether sleep or pain management motives influence their choices.

    These findings go beyond simply asking if someone uses cannabis; they highlight that the pattern and variety of consumption may better identify those at higher risk of frequent use and addiction.

    However, the study cannot establish causation—it’s unclear whether using multiple forms leads to addiction or if heavier users are simply more likely to try various methods. Since data relied on self-reporting, some participants might not have fully disclosed their use, but the large, nationally representative sample underscores the importance of further investigation, especially as product options expand and become more accessible.

    Source: NYU Langone Health

  • Cannabis Doesn’t Affect Men’s Testosterone or Fertility

    Cannabis Doesn’t Affect Men’s Testosterone or Fertility

    For years, scientists have debated how cannabis impacts male reproductive health. With increasing cannabis use around the world, questions about its long-term effects on hormones and fertility have gained urgency. Some research suggests that cannabis might negatively affect sperm quality and lower testosterone levels, while other studies find little evidence supporting these claims. Due to these conflicting results, researchers have been searching for clearer insights.

    A recent study from the University of Geneva (UNIGE) in Switzerland offers a surprising new perspective. The research indicates that, in young men, cannabis use does not decrease testosterone levels—in fact, it might even boost testosterone production in the testes. The findings were published in the journal Communications Medicine.

    The study was conducted by scientists from the University of Geneva in partnership with the Swiss Center for Applied Human Toxicology. Their objective was to better understand how cannabis influences the body’s hormonal systems, especially those involved in male reproduction.

    Male fertility is affected by many factors, including hormone levels, sperm production, lifestyle choices, age, and overall health. Testosterone, one of the key male sex hormones, plays a central role in sexual development, muscle growth, bone density, and reproductive function. Because of its importance, researchers have long wondered whether cannabis use can alter testosterone levels.

    Previous research has yielded mixed results. Some studies found that cannabis users had lower sperm counts, reduced motility, and poorer overall sperm quality. Others saw little to no direct effect of cannabis on reproductive hormones. One challenge in these studies was that many focused only on individual hormones, providing an incomplete picture.

    In this new investigation, the researchers took a broader approach. They analyzed blood samples from 94 Swiss military recruits aged 18 to 23, split evenly between 47 confirmed cannabis users and 47 non-users. Rather than targeting a single hormone, they measured hundreds of steroid hormones and related compounds circulating in the blood. This comprehensive analysis allowed for a deeper understanding of how cannabis might influence the endocrine system, which regulates many vital body functions.

    Results showed that cannabis users had testosterone levels approximately 23% higher than those of non-users. Further examination revealed that this increase stemmed specifically from the testes. Hormones produced by the adrenal glands, which also produce androgens, did not show similar changes. The findings suggest that cannabis may directly impact Leydig cells—the specialized cells inside the testes responsible for testosterone production.

    The study also identified two hormone-related substances, hydroxyprogesterone and dihydroprogesterone, which are derived from progesterone—a hormone involved in reproductive health. These compounds were significantly elevated in cannabis users and may serve as new biological markers of regular cannabis use. Tracking these markers could help researchers better understand how cannabis influences the hormonal system and monitor hormone-related changes over time.

    However, higher testosterone levels do not automatically translate into increased fertility. The relationship between testosterone and reproductive health is complex. Fertility depends on sperm count, motility, morphology, hormone balance, and various other biological factors. An increase in testosterone alone does not guarantee improved fertility.

    The researchers proposed several possible reasons for the observed testosterone increase. One theory is that the body might be compensating for reduced sensitivity of certain hormone receptors caused by cannabis exposure. Another possibility is that young men with naturally higher testosterone levels may be more inclined to engage in risk-taking behaviors, including cannabis use.

    As an observational study, it cannot establish causality—only an association between cannabis use and higher testosterone levels. The most significant strength of this research lies in its comprehensive analysis of numerous hormones rather than just a single measurement, offering a more complete view of cannabis’s potential effects on the endocrine system.

    Nonetheless, the study has limitations. Its sample size was relatively small, all participants were young Swiss men, and the findings may not apply to older individuals or those from different populations.

    Overall, these results challenge the common belief that cannabis automatically reduces testosterone levels. They also emphasize how much remains unknown about the relationship between cannabis and male fertility. Further long-term research is necessary to determine if certain levels of cannabis exposure could become harmful or if the hormonal changes observed have significant impacts on reproductive health.

    This study was published in Communications Medicine.

    Source: University of Geneva.

  • Using Cannabis to Escape Pain Could Trigger Paranoia

    Using Cannabis to Escape Pain Could Trigger Paranoia

    Many individuals turn to cannabis as a way to unwind, ease stress, improve sleep, or manage emotional pain. As its acceptance and legalization grow across various regions, more people are also using it to help with anxiety, depression, trauma, or physical discomfort. However, emerging research indicates that self-medicating with cannabis could pose serious mental health risks.

    A significant new study conducted by researchers at King’s College London and the University of Bath reveals that those who use cannabis to cope with emotional distress, stress, or trauma may face a substantially increased risk of developing paranoia and other mental health issues later on. These findings contribute to a growing body of scientific concern about the impact of frequent cannabis use on brain health.

    The research, published in BMJ Mental Health and Psychological Medicine, was part of the Cannabis & Me project, one of the largest studies of its kind examining cannabis use and mental health in the general population. Scientists examined data from over 3,300 adults who either currently used cannabis or had used it in the past. None of the participants had a diagnosed psychotic disorder when they enrolled. The goal was to understand why individuals started using cannabis and how it affected their mental health over time.

    Results showed a clear trend: users who initially consumed cannabis to alleviate anxiety, depression, physical pain, emotional stress, or mild psychotic symptoms had significantly higher levels of paranoia than those who used cannabis mainly for entertainment, curiosity, or social reasons. Paranoia involves excessive suspicion or fear of others, such as believing that people are watching or trying to harm you, often without any real evidence. Severe paranoia can be distressing and interfere with daily functioning.

    The study also discovered that people who used cannabis for self-soothing tended to consume larger amounts of THC, the main psychoactive component responsible for the “high.” On average, participants consumed about 206 units of THC weekly—roughly equivalent to 10 to 17 joints, depending on potency. Those using cannabis to manage anxiety or depression typically consumed even more.

    Modern cannabis products are much stronger than in the past, with many strains and concentrates containing very high THC levels, which may heighten the risk of adverse mental health effects. The study also examined the relationship between childhood trauma and paranoia. Over half of the participants reported experiencing some form of trauma as children, including emotional or physical abuse, bullying, neglect, or conflicts at home. Those with childhood trauma histories were more prone to develop paranoia later, and cannabis use appeared to amplify this connection. In particular, emotional abuse and household conflicts were strongly associated with increased cannabis use and higher paranoia scores.

    Dr. Giulia Trotta, a lead researcher, explained that this study is the first large-scale project to closely analyze how childhood trauma, cannabis consumption, and paranoia interact within the general population. The findings suggest that cannabis might intensify the psychological effects of past trauma for some individuals.

    Professor Marta Di Forti, senior author and expert in psychosis research, emphasized that many people attempt to cope with emotional or physical pain through cannabis. Yet, the evidence indicates that this approach may sometimes backfire, increasing mental health risks instead of alleviating them.

    As cannabis use becomes more common worldwide—and attitudes toward it shift toward viewing it as safe or medicinal—these findings highlight the importance of understanding the full picture. While some users may experience temporary relief, heavy or long-term consumption could increase vulnerability to anxiety, paranoia, dependence, and psychotic-like symptoms in predisposed individuals.

    The research does not establish that cannabis directly causes paranoia in everyone, as mental health is complicated and influenced by genetics, trauma, stress, environment, and other factors. Nonetheless, the strong correlation between self-medication with cannabis and paranoia raises important concerns.

    The scientists advocate for better public education regarding cannabis and mental health, and they recommend that healthcare providers inquire about patients’ trauma histories and cannabis use when assessing symptoms like paranoia or anxiety. Experts also advise that those suffering from trauma, depression, or anxiety might benefit more from evidence-based treatments such as therapy, support systems, or medical interventions rather than relying heavily on cannabis.

    As legalization spreads, understanding the potential benefits and harms of cannabis becomes increasingly vital. The recent findings suggest that attempting to escape emotional pain or trauma through cannabis may not always bring relief and could, in some cases, worsen mental health issues over time.